Dr. Mohammad Uddin

Assistant Professor of Pharmaceutical Sciences

Education

  • B.S., Jahangirnagar University, Dhaka, Bangladesh
  • M.S., Jahangirnagar University, Dhaka, Bangladesh
  • M.S., Emory University
  • Ph.D., Mercer University

Courses

  • PHA 337  Biopharmaceutics and Pharmacokinetics
  • PHA 338  Pharmaceutics and Medicinal Chemistry
  • PHA 401  Pharmaceutics Laboratory
  • PHA 535  Gastrointestinal Disorders

Research Interests

My research interest focuses on developing quickly soluble film-based delivery system to deliver small molecule drug or vaccine via buccal or sublingual administration. My research seeks to develop highly efficient, cost effective and patient compliant film dosage form of vaccines for cervical cancer. Film-based vaccines are prepared using bio-degradable, bio-compatible and non-antigenic polymer. Then the physicochemical properties such as solubility, endurance, tensile strength, thickness, etc. of the film are determined and then ensued by an in vitro dissolution study and in vivo animal study to evaluate the efficacy of the formulation.

Publications

Uddin MN, Basak D, Hopefl R and Minofar B. Potential application of ionic liquids (ILs) in pharmaceutical dosage form for vaccine and small molecule drug delivery system – Journal of Pharmacy & Pharmaceutical Sciences, 23(1), 158-176. 2019. https://doi.org/10.18433/jpps30965

Uddin MN, Henry B, Carter KD, Roni MA, and Kouzi, SA. A Novel Formulation Strategy to Deliver Combined DNA and VLP Based HPV Vaccine – J Pharm Pharm Sci (www.cspsCanada.org) 22: 536 – 547, 2019.

Uddin MN, Allon A, Roni MA, Kouzi S – Overview and Future Potential of Fast Dissolving Buccal Films as Drug Delivery System for Vaccines – J Pharm Pharm Sci, (www.cspsCanada.org) 22: 388 – 406, 2019.

Kouzi SA, Nicholas JD, Wright, Amie JD, and Uddin MN – Fumonisins: Mechanisms of Action and Effects on Human and Animal Health – EC Pharmacology and Toxicology, 6 (4): 187-208, 2018.

Uddin MN, Cotta KI and D’Souza MJ – Stability determination and evaluation of gamma irradiated nuclear-factor-kB antisense microsphere – Journal of Drug Design Development and Therapy, (DOI: 10.15406/mojddt.2016.01.00001) 1(1): 1-6, 2016

Uddin MN, Patel NJ, Bhowmik T, D’Souza B, Akalkotkar A, Etzlar F, Oettinger CW, D’Souza MJ. (2013). Enhanced bioavailability of orally administered antisense oligonucleotide to nuclear factor kappa B mRNA after microencapsulation with albumin. J Drug Target. 21(5):450-7.

Bhowmik, T, D’Souza B., Uddin MN and D’Souza M.J., (2012) Oral delivery of microparticles containing plasmid DNA encoding hepatitis-B surface antigen. J Drug Target, 20, 364-71.

D’Souza B, Bhowmik T, Uddin MN, Oettinger C, D’Souza M. (2015). Development of cyclodextrin-based sustained release microparticles for oral insulin delivery. Drug Dev Ind. Pharm. Aug;41(8):1288-93.

D’Souza B, Bhowmik T, Uddin MN, Oettinger C, and D’Souza MJ -Development of b-cyclodextrin-based sustained release microparticles for oral insulin delivery- Drug Development and Industrial Pharmacy, 41(8): 1288-1293, 2015.

Patel NJ, Addo R, Uddin MN, D’Souza MJ, and Jobe L. – The effect of antisense to NF-kB in an albumin microsphere formulation on the progression of left-ventricular remodeling associated with chronic volume overload in rats. Journal of Drug Targeting, 3: 1-9, 2014.

Panicker G, Vo T, Rajvandari I, Uddin MN, Mangalathu R, Unger ER, and D’Souza MJ – Development of a microparticulate HPV vaccine for oral delivery. Supplement, The FASEB Journal, 27(1): 2013.

Etzler FM and Uddin MN – Powder Technology and Pharmaceutical Development: Particle Size and Particle Adhesion- Powder and Particle Journal, 30, 125-143, 2013.

Uddin MN, Oettinger CW, Bhowmik T, D’Souza B and D’Souza MJ – Enhanced bioavailability of Antisense to NF-ĸB Oligonucleotides after microencapsulation. Journal of Drug Targeting, 21(5): 450-457, 2013.

Uddin MN, Siddiq A, Oettinger CW, and D’Souza MJ – Potentiation of Pro- inflammatory cytokine suppression and survival by microencapsulated dexamethasone in the treatment of experimental sepsis.  Journal of Drug Targeting, 2011 Nov; 19(9):752-60.

Siwale RC, Oettinger CW, Pai SB, Addo R, Uddin MN, Siddig A, D’Souza MJ – Formulation and characterization of Catalase in albumin microspheres.  Journal of Microencapsulation, 24 (4): 337-348, 2009.

Uddin MN, Duc P. Do, Pai SB, Gayakwad S, Oettinger CW and D’Souza MJ – A Methodology for Quantitation and Characterization of Oligonucleotides in Albumin Microspheres.  The Analyst, 134(7): 1483-1492, 2009.

Bhowmik T, Uddin MN, D’Souza B and D’Souza MJ – Oral Delivery of Microparticles containing Plasmid DNA encoding Hepatitis B Surface Antigen- Journal of drug Targeting, 20(4):  364-71, 2012.

Hagen KS and Uddin MN– A Continuous Symmetry Measure of [4Fe-4S]+ core distortions and analysis of supramolecular synthons in crystal structures of (Et4N)3[Fe4S4Cl4]•Et4NCl at 100 & 295K.  Inorganic Chemistry, 47(24): 11807-11815, 2008.

Janiak C, Chamayou AC, Uddin AKM, Uddin MN, Hagen KS and Enamullah M- Polymorphs, enantiomorphs, chirality and helicity in [Rh{N,O}(.4-cod)] complexes with {N,O} = salicylaldiminato Schiff base or aminocarboxylato ligands. Dalton Transaction, 19: 3698-3709, 2009.

Enamullah M, Uddin AKM and Uddin MN, – Synthesis and spectroscopic characterization of Rh(I)-1,5-cyclooctadiene complexes containing the o-aminobenzoic acid or o-aminophenol as co-ligands. J. Bangladesh Chem.  Soc., 21 (1): 28-35, 2008.

Enamullah M, Uddin MN and Linert W – Synthetic and spectroscopic characterization of Rh(I)-(S)-amino acid complexes with diphosphine and triphosphine ligands. – Journal of Coordination Chemistry. 60 (21): 2309-2318, 2007.

Enamullah M, Kabir M, and Uddin MN – Spectroscopic studies of the low -spin neutral Iron(II) -complexes with deprotonated. 4-X-2,6-bis(benzimidazol-2’yl)pyridine (X = H, OH and Cl). Journal of Bangladesh Chemical Society, 20(2): 163-171, 2007