Patents and Publications

Patents

  1. Joshi VM, Mandaogade PM, Chougule MB, Jain GK, International Patent, pharmaceutical compositions of bupropion, WO/2008/026044, 2008
  2. Joshi VM, Mandaogade PM, Chougule MB, Jain GK, International Patent, Stable pharmaceutical compositions of bupropion, WO/2008/129465, 2008
  3. Joshi VM, Mandaogade PM, Chougule MB, Jain GK, pharmaceutical composition comprising bupropion or salt thereof and stabilizer, Indian patent, 771/MUM/2007 A, 2007
  4. Mandaogade PM, Joshi VM, Chougule MB, Srivastav S., Jain GK, , G. K. Jain, Stabilized pharmaceutical composition of bupropion or salt thereof, Indian patent, 1389/MUM/2006 A, 2006
  5. Joshi VM, Chougule MB, Mandaogade PM Jain GK,, Melt-granulated bupropion sustained release formulation, Indian patent, 1375/MUM/2006 A, 2006
  6. Misra A, Chougule MB, Ganesh S., and Padhi B, Indian patent, Aerodynamically light porous dry powder inhaler formulations for targeted pulmonary deposition (2006 no. 953/MUM/2006
  7. Misra A, Chougule MB, Padhi B, Ganesh S. Indian patent, Enhancement of pulmonary therapeutic index of drugs from dry powder inhaler formulations, 729/ MUM /2005
  8. Misra A, Chougule M, Padhi B, Indian patent, Engineered monodisperse inhalation powders for effective treatment of lung diseases, 228/MUM/2005
  9. Chougule MB, Bachmann AS, Development of ligand-mediated nanocarrier system of DFMO alone and/or in combination with chemotherapeutic drug for the treatment of cancer, U.S. provisional application No. 61/558,368

Selected Publications 

  1. Marathe S, Joshi R, Yang R, Shadambikar G, Bachmann AS, Chougule MB*. Integration of Design of Experiments for the Development and Evaluation of Sulfasalazine-Loaded Hybrid Albumin Chitosan-Based Polymeric Nanocarriers. AAPS PharmSciTech. 2025 Jul 14;26(6):192.
  2. Kashikar R, Kotha AK, Shrestha R, Channappanavar R, Chougule MB*, Formulation and in-vitro testing of nebulized extended-release antiviral Camostat Mesylate loaded nanosuspension product for the treatment of SARS-CoV-2 Infection, AAPS PharmSciTech, 2025, 26(5), 139, 1-18
  3. Kashikar R, Kotha AK, Shrestha R, Channappanavar R, Chougule MB*, Design of experiments using Box Behnken Design in the development, characterization, mathematical modeling, and evaluation of tung targeted nebulized antiviral Camostat Mesylate loaded pegylated nanosuspension product, Journal of Drug Delivery Science and Technology, 2024, Volume 98, 105810.
  4. Harris HM, Boyet KL, Liu H, Dwivedi R, Ashpole NM, Tandon R, Bidwell GL 3rd, Cheng Z, Fassero LA, Yu CS, Pomin VH, Mitra D, Harrison KA, Dahl E, Gurley BJ, Kotha AK, Chougule MB, Sharp JS*. Safety and pharmacokinetics of intranasally administered heparin. Pharm Res. 2022 Mar;39(3):541-551.
  5. Vinjamuri BP, Papachrisanthou K, Haware RV, Chougule MB*. Gelatin solution pH and incubation time influences the size of the nanoparticles engineered by desolvation. Journal of Drug Delivery Science and Technology2021, 63, 02423
  6. Shahin HI, Vinjamuri BP, Mahmoud AA, Shamma RN, Mansour SM, Ammar HO, Ghorab MM, Chougule MB*, Chablani L. Design and evaluation of novel inhalable sildenafil citrate spray-dried microparticles for pulmonary arterial hypertension. J Control Release. 2019 Mar 30. pii: S0168-3659(19)30189-0.
  7. Shadambikar, Marathe S, Ji Nan , Bandari S, Chougule MB, Repka M*. Formulation Development of Itraconazole Loaded PEGylated Nano-Lipid Carriers for Pulmonary Aspergillosis Using Hot Melt Extrusion Technology, International Journal of Pharmaceutics, 2021, Volume 3, December 2021, 100074
  8. Chandrasiri I, Abebe DG, Yaddehige ML, Dal Williams JS, Zia MF, Dorris A, Barker A, Vinjamuri, BP, Le N, Gayton JN, Chougule MB, Hammer NI, Flynt A, Delcamp JH, Watkins D Self-Assembling PCL-PAMAM Linear Dendritic Block Copolymers (LDBCs) for Bioimaging and Phototherapeutic Applications. ACS Applied Bio Materials, 2021, 3(9), 5664-5677
  9. Yang R, Nam K, Kim SW, Turkson J, Zou Y, Zuo YY, Haware RV, Chougule MB*, Factorial Design Based Multivariate Modeling and Optimization of Tunable Bioresponsive Arginine Grafted Poly(cystaminebis(acrylamide)-diaminohexane) Polymeric Matrix Based Nanocarriers. Mol Pharm.2017 Jan 3;14(1):252-263.
  10. España-Serrano L and Chougule MB*. Enhanced anticancer activity of PF-04691502, a dual PI3K/mTOR inhibitor, in combination with VEGF siRNA against non-small cell lung cancer. Molecular Therapy – Nucleic Acids (Nature publishing group), 2016, Nov 15;5(11):e384
  11. Youngren-Ortiz SR, Gandhi NS, España-Serrano L, Chougule MB*. Aerosol Delivery of siRNA to the Lungs. Part 1: Rationale for Gene Delivery Systems. Kona: powder science and technology in Japan. 2016;33:63.
  12. Tekade RK, Youngren-Ortiz SR, Yang H, Haware R, Chougule MB*. Albumin-chitosan hybrid onconase nanocarriers for mesothelioma therapy. Cancer Research. 2015;75(15 Supplement):3680.
  13. Tekade RK, Youngren-Ortiz SR, Yang H, Haware R, Chougule MB*. Designing Hybrid Onconase NCs for Mesothelioma Therapy: A Taguchi Orthogonal Array and Multivariate Component Driven Analysis. Molecular Pharmaceutics. 2014; 11(10):3671-83.
  14. Chougule MB*, Patel AR, Patlolla R, Jackson T, Singh M*. Epithelial transport of Noscapine across cell monolayer and influence of absorption enhancers on in vitro permeation and bioavailability: implications for intestinal absorption. Journal of drug targeting. 2014; 22(6):1-11.
  15. Patel AR, Chougule MB, Lim E, Francis FP, Safe S, and Singh M*, Theranostic tumor homing NCs for the treatment of lung cancer. Nanomedicine. 2014; 10(5):1053-63.
  16. Youngren SR, Tekade RK, Gustilo B, Hoffmann PR, and Chougule MB*, STAT6 siRNA matrix-loaded gelatin NCs: formulation, characterization, and ex vivo proof of concept using adenocarcinoma cells. BioMed Research International. 2013; 2013:858946.
  17. Patel AR, Chougule MB, Townley I, Patlolla R, Wang G, Singh M*. Efficacy of aerosolized celecoxib encapsulated nanostructured lipid carrier in non-small cell lung cancer in combination with docetaxel. PHARM RES. 2013; 30(5):1435-46.
  18. Tekade, R.K. and Chougule MB*, Formulation development and evaluation of hybrid NC for cancer therapy: Taguchi orthogonal array based design. Biomed Res Int, 2013. 2013:712678.
  19. Chougule MB, Patel AR, Sachdeva P, Jackson T, Singh M*. Anti-cancer activity of noscapine, an opioid alkaloid in combination with cisplatin in human non-small cell lung cancer. Lung Cancer, 2011, 71(3):271-82.  
  20. Chougule MB, Patel AR, Jackson T, Singh M*. Antitumor activity of noscapine in combination with Doxorubicin in triple negative breast cancer. PLoS One. 2011; 6(3):e17733.
  21. Ichite N, Chougule MB, Patel AR, Jackson T, Safe S, Singh M*. Inhalation delivery of a novel diindolylmethane derivative for the treatment of lung cancer. Molecular Cancer Therapeutics. 2010; 9(11):3003-14. The first two authors contributed equally.
  22. Patlolla R, Chougule MB, Patel AR, Jackson T, and Singh M*. Celecoxib encapsulated nanostructured lipid carrier system for pulmonary delivery. Journal of Controlled Release. 2010; 144(2):233-41.